2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-181544
    SB5-171
    		Inhibitor
    SB5-171 is a covalent PfCLK3 inhibitor with IC50 values of 10-12 nM. SB5-171shows antiparasitic activity. SB5-171 can be used for the research of malaria.
    SB5-171
  • HY-B1467R
    Domiphen bromide (Standard)
    		Inhibitor
    Domiphen bromide (Standard) is the analytical standard of Domiphen bromide (HY-B1467). This product is intended for research and analytical applications. Domiphen bromide is a cationic active quaternary ammonium salt and also an inhibitor of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin. Domiphen bromide has multiple activities such as antibacterial, antimalarial, and disinfectant properties, and it is also a synergist of Colistin (HY-113678). Domiphen bromide can be used as a chemical preservative and a cationic surfactant, and it can also be used in the research of bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers.
    Domiphen bromide (Standard)
  • HY-181010
    HDAC1-IN-12
    		Inhibitor
    HDAC1-IN-12 is a Plasmodium falciparum HDAC1 (PfHDAC1) inhibitor with an IC50 of 4.1 nM against Pf3D7. HDAC1-IN-12 inhibits PfHDAC1, upregulates histone H3 acetylation in P. falciparum parasites, downregulates malaria invasion-related gene expression, and exhibits favorable safety profiles, improved physicochemical properties, and potent in vivo antimalarial activity. HDAC1-IN-12 can be used for the research of malaria.
    HDAC1-IN-12
  • HY-W714863
    Arohynapene B
    		Inhibitor
    Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria tenella.
    Arohynapene B
  • HY-W777995
    Clindamycin B
    		Inhibitor
    Clindamycin B is a derivative of Clindamycin (HY-B1455).
    Clindamycin B
  • HY-119556
    Butonate
    		Inhibitor
    Butonate is an insecticide. Butonate is an orally active anthelmintic.
    Butonate
  • HY-137968
    Avermectin B1a aglycon
    		Inhibitor
    Avermectin B1a aglycon is an aglycone derivative of Avermectin B1a (HY-15308), an antiparasitic agent that paralyzes nematodes. Avermectin B1a aglycon hyperpolarizes P. crassipes muscle fibers, with a minimum effective concentration of 0.1 μM.
    Avermectin B1a aglycon
  • HY-W437569
    Melicopine
    		Inhibitor
    Melicopine is an alkaloid found in Z. simulans with antimalarial and anticancer activities. It exhibits inhibitory activity against chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains of P. falciparum, with IC50 values of 29.7 and 33.7 µg/mL, respectively. Melicopine is cytotoxic to prostate cancer cells PC-3M and LNCaP (IC50 values of 47.9 and 37.8 µg/mL), but has no effect on non-cancerous HEK293 cells (IC50 greater than 100 µg/mL). Melicopine holds promise for research in anticancer and anti-infection fields.
    Melicopine
  • HY-D0143A
    Quinine dihydrochloride
    		Inhibitor
    Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
    Quinine dihydrochloride
  • HY-B0295R
    Chloroxine (Standard)
    		Inhibitor
    Chloroxine (Standard) is the analytical standard of Chloroxine. This product is intended for research and analytical applications. Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp.
    Chloroxine (Standard)
  • HY-175362
    WEHI-326
    		Inhibitor
    WEHI-326 is a potent antimalarial agent targeting Plasmodium falciparum ROM8 and CSC1 proteins (IC50=0.006 μM). WEHI-326 is promising for research of malaria.
    WEHI-326
  • HY-117986
    AB 3217-A
    		Inhibitor
    AB 3217-A, an anti-mite substance, can be isolated from the fermentation broth of a streptomycete strain.
    AB 3217-A
  • HY-119707
    TDR 32750
    		Inhibitor
    TDR 32750 is an antimalarial agent. TDR 32750 inhibits P. falciparum activity with an ED50 value of 0.014 μM.
    TDR 32750
  • HY-174130
    PI4Kβ/PKG-IN-1
    		Inhibitor
    PI4Kβ/PKG-IN-1 (Compound 19) is an orally active dual inhibitor targeting Plasmodium phosphatidylinositol 4-kinase beta (PI4Kβ) and cGMP-dependent protein kinase (PKG). PI4Kβ/PKG-IN-1 exhibits potent antiplasmodial activity. PI4Kβ/PKG-IN-1 is promising for research of malaria.
    PI4Kβ/PKG-IN-1
  • HY-183178
    Teroxalene
    		Inhibitor
    Teroxalene is a piperazine-based Schistosomicide. Teroxalene is used for the research of schistosomiasis.
    Teroxalene
  • HY-B1099R
    Hycanthone (Standard)
    		Inhibitor
    Hycanthone (Standard) is the analytical standard of Hycanthone. This product is intended for research and analytical applications. Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.
    Hycanthone (Standard)
  • HY-185218
    WR 146459
    		Inhibitor
    WR 146459 is an orally active 9-phenanthrenecarbinol and antimalarial agent. WR 146459 bears a 2-piperidyl substituent on its 9-carbinol moiety. WR 146459 inhibits hypoxanthine uptake by Plasmodium falciparum strains, reducing parasite viability. WR 146459 can be used for the research of malaria.
    WR 146459
  • HY-155401
    Antitrypanosomal agent 18
    		Inhibitor
    Antitrypanosomal agent 18 (compound 8b) is a nitrofuran derivative has strong trypanocidal activity in vitro with an IC50 value of 0.03 μM.
    Antitrypanosomal agent 18
  • HY-N12232
    Carbazomycin D
    		Inhibitor
    Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC50 > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC50s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively.
    Carbazomycin D
  • HY-175506
    RyRs activator 6
    		Inhibitor
    RyRs activator 6 (compound C3) is a ryanodine receptor (RyRs) activator that activates calcium release in insect neurons. RyRs activator 6 has insecticidal activity.
    RyRs activator 6
Parasite Isoform Comparison

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